Altered functional magnetic resonance imaging resting-state connectivity in periaqueductal gray networks in migraine
نویسندگان
چکیده
منابع مشابه
Altered functional magnetic resonance imaging resting-state connectivity in periaqueductal gray networks in migraine.
OBJECTIVE The periaqueductal gray matter (PAG), a known modulator of somatic pain transmission, shows evidence of interictal functional and structural abnormalities in migraineurs, which may contribute to hyperexcitability along spinal and trigeminal nociceptive pathways, and lead to the migraine attack. The aim of this study was to examine functional connectivity of the PAG in migraine. METH...
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متن کاملAltered periaqueductal gray resting state functional connectivity in migraine and the modulation effect of treatment
The aims of this study were to 1) compare resting state functional connectivity (rs-fc) of the periaqueductal gray (PAG), a key region in the descending pain modulatory system (DPMS) between migraine without aura (MwoA) patients and healthy controls (HC), and 2) investigate how an effective treatment can influence the PAG rs-fc in MwoA patients. One hundred MwoA patients and forty-six matched H...
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Background This study used machine-learning techniques to develop discriminative brain-connectivity biomarkers from resting-state functional magnetic resonance neuroimaging ( rs-fMRI) data that distinguish between individual migraine patients and healthy controls. Methods This study included 58 migraine patients (mean age = 36.3 years; SD = 11.5) and 50 healthy controls (mean age = 35.9 years; ...
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ژورنال
عنوان ژورنال: Annals of Neurology
سال: 2011
ISSN: 0364-5134
DOI: 10.1002/ana.22537